What is lithium toxicity? Show
Lithium toxicity is another term for a lithium overdose. It occurs when you take too much lithium, a mood-stabilizing medication used to treat bipolar disorder and major depressive disorder. Lithium helps reduce episodes of mania and lowers the risk of suicide in people with these conditions. The right dosage of lithium varies from person to person, but most people are prescribed between 900 milligrams (mg) to 1,200 mg per day, in divided doses. Some people take more than 1,200 mg per day, especially during acute episodes. Others may be more sensitive to lower doses. A safe blood level of lithium is 0.6 and 1.2 milliequivalents per liter (mEq/L). Lithium toxicity can happen when this level reaches 1.5 mEq/L or higher. Severe lithium toxicity happens at a level of 2.0 mEq/L and above, which can be life-threatening in rare cases. Levels of 3.0 mEq/L and higher are considered a medical emergency. People taking lithium need to carefully monitor how much they take it and when. It’s easy to accidentally overdose on lithium by taking an extra pill, mixing it with other medications, or not drinking enough water. In 2014, for example, there were 6,850 reported cases of lithium toxicity in the United States. Lithium toxicity is usually caused by taking more than your prescribed dose of lithium, either at once or slowly over a long period of time. There are three main types of lithium toxicity, each with different causes:
If you think someone is at immediate risk of self-harm, overdosing, or hurting another person:
If you or someone you know is considering suicide, get help from a crisis or suicide prevention hotline. Try the National Suicide Prevention Lifeline at 800-273-8255. Sensitivities and interactions with lithiumSome people are more sensitive to lithium and may experience symptoms of lithium toxicity at lower levels than others. This is especially true in people who are older or dehydrated. It’s also more likely in people with cardiovascular and kidney problems. Certain foods or drinks may also affect lithium concentrations in the body. It’s best to not adjust the following unless monitored by a doctor: INSERT LONG LIST FORMAT:
In addition, taking lithium with other medications can also increase your risk of lithium toxicity. If you take lithium, make sure you talk to your doctor before using:
Mild lithium toxicity is often difficult to diagnose because its symptoms are similar to those of many other conditions. Your doctor will likely start by asking you some questions about how much lithium you take, as well as how often you take it. Be sure to tell your doctor about all of your symptoms, any recent illnesses, and whether you’re taking any other medications, including vitamins, supplements, and even teas. They may also use one or a combination of the following tests:
If you’re taking lithium and experience any of the symptoms of lithium toxicity, seek immediate treatment or call the Poison Control Center hotline at 1-800-222-1222 for instructions on what to do. There’s no specific antidote for lithium toxicity. Mild toxicityMild lithium toxicity usually goes away on its own when you stop taking lithium and drink some extra fluids. However, your doctor may still want to keep an eye on you while you recover. Moderate to severe toxicityModerate to severe lithium toxicity usually requires additional treatment, such as:
Lithium toxicity can have lasting effects, so it’s important to seek medical attention immediately if you think you may have it. Avoid home remedies, such as activated charcoal, which doesn’t bind to lithium. When caught early, lithium toxicity is often treatable with extra hydration and reducing your dosage. However, moderate to severe lithium toxicity is a medical emergency and might require additional treatment, such as stomach pumping. If you take lithium, make sure you know the signs of an overdose and keep the number for poison control (1-800-222-1222) handy in your phone. Contact your doctor if you have any concerns about medication or food interactions that might occur while you take lithium. Which of the following are side effects from taking lithium Select all that apply?What are possible side effects of lithium?. Headache.. Nausea or vomiting.. Diarrhea.. Dizziness or drowsiness.. Changes in appetite.. Hand tremors.. Dry mouth.. Increased thirst.. Which of the following instructions should you give to a patient taking lithium carbonate?Swallow the whole or split tablet without crushing or chewing. Drink 8 to 12 glasses (8 ounces or 240 milliliters each) of water or other fluid each day, and eat a healthy diet with normal amounts of salt (sodium) as directed by your doctor or dietician while taking this medication.
What are the symptoms of lithium carbonate toxicity?Symptoms of lithium toxicity include severe nausea and vomiting, severe hand tremors, confusion, and vision changes.. Headache.. Nausea or vomiting.. Dizziness or drowsiness.. Diarrhea.. Changes in appetite.. Hand tremors.. Dry mouth.. Increased thirst.. Which of the following are potential side effects of lithium?Side Effects. Confusion, poor memory, or lack of awareness.. fast, pounding, or irregular heartbeat or pulse.. frequent urination.. increased thirst.. slow heartbeat.. stiffness of the arms or legs.. troubled breathing (especially during hard work or exercise). weight gain.. |