Genetics
Show The karyotype from an individual with Down’s syndrome (trisomy 21). Image credit: Wessex Reg. Genetics Centre, Wellcome Images Biology
Symptoms
People with Down’s syndrome tend to have mild to moderate intellectual disability.
People with Down’s syndrome can live into their 40s and 50s. Image credit: Shutterstock Diagnosis
Treatment
People with Down’s syndrome can lead relatively normal and successful lives. Image credit: Shutterstock This page was last updated on 2021-07-21 What happens if chromosome 21 has an extra?Down syndrome is a genetic disorder caused when abnormal cell division results in an extra full or partial copy of chromosome 21. This extra genetic material causes the developmental changes and physical features of Down syndrome.
What causes an extra chromosome 21?The abnormality usually occurs in egg cells, but it occasionally occurs in sperm cells. An error in cell division called nondisjunction results in a reproductive cell with an abnormal number of chromosomes. For example, an egg or sperm cell may gain an extra copy of chromosome 21.
What condition results when a child is born with an extra chromosome on the twenty first pair?Also known as Down syndrome, trisomy 21 is a genetic condition caused by an extra chromosome. Most babies inherit 23 chromosomes from each parent, for a total of 46 chromosomes. Babies with Down syndrome however, end up with three chromosomes at position 21, instead of the usual pair.
What is Down's syndrome?Down's syndrome is when you're born with an extra chromosome. You usually get an extra chromosome by chance, because of a change in the sperm or egg before you're born. This change does not happen because of anything anyone did before or during pregnancy.
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