. When the Testoderm form of testosterone is ordered to treat hypogonadism in a teenage boy, which instructions by the nurse are correct? (Select all that apply.) Show a. Place the patch on clean, dry skin on the back, upper arms, abdomen, or thighs. b. Place the patch on clean, dry scrotal skin that has been shaved. c. Place the patch on clean, dry scrotal skin, but do not shave the skin first. d. Place the patch on any clean, dry, nonhairy area of the body. e. Remove the old patch before applying a new patch. Which drug is contraindicated in osteoporosis?Antiepileptic Drugs
The medications most commonly associated with osteoporosis include phenytoin, phenobarbital, carbamazepine, and primidone. These antiepileptic drugs (AEDs) are all potent inducers of CYP-450 isoenzymes.
Why are bisphosphonates contraindicated in renal failure?Bisphosphonates, which are excreted via the kidneys, may accumulate in patients with diminished renal function, and toxicity may occur. There have been several reports of acute renal toxicity following bisphosphonate treatment.
What are the contraindications of bisphosphonates?Contraindications to bisphosphonates include: History of hypersensitivity to the bisphosphonate. Hypocalcemia. Chronic kidney disease with a glomerular filtration rate of less than 30 to 35 mL/min.
Can you take Fosamax with kidney disease?To minimize the risk of chronic kidney disease (CKD) progressing to end-stage renal disease (ESRD), such osteoporosis medications as alendronate (Fosamax) and ibandronate (Boniva) are contraindicated in individuals whose glomerular filtration rate (GFR) is <30%.
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Which medication is contraindicated in patients who have osteoporosis and a history of renal dysfunction?
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