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Biology: The Dynamics of Life (California)1st EditionBiggs, Hagins 1,671 solutions How does a normal cell become a cancer cell?DNA repair genes are involved in fixing damaged DNA. Cells with mutations in these genes tend to develop additional mutations in other genes and changes in their chromosomes, such as duplications and deletions of chromosome parts. Together, these mutations may cause the cells to become cancerous.
What is the most likely reason cells become cancerous?Cells become cancerous after mutations accumulate in the various genes that control cell proliferation. According to research findings from the Cancer Genome Project, most cancer cells possess 60 or more mutations.
What causes a normal cell to turn cancerous how is it different from a normal cell?Normal cells have normal DNA and a normal number of chromosomes. Cancer cells often have an abnormal number of chromosomes and the DNA becomes increasingly abnormal as it develops a multitude of mutations. Some of these are driver mutations, meaning they drive the transformation of the cell to be cancerous.
Which of the following mutated proteins is most likely to cause a cell to become cancerous?The most commonly mutated gene in people with cancer is p53 or TP53. More than 50% of cancers involve a missing or damaged p53 gene. Most p53 gene mutations are acquired. Germline p53 mutations are rare, but patients who carry them are at a higher risk of developing many different types of cancer.
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Which of the following conditions will most likely cause a normal body cell to become a cancer cell?
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