If you're seeing this message, it means we're having trouble loading external resources on our website. Show If you're behind a web filter, please make sure that the domains *.kastatic.org and *.kasandbox.org are unblocked. Copyright 2022 Learn By Doing, Inc. *AP® and Advanced Placement® are registered trademarks of the College Board, which was not involved in the production of, and does not endorse, this product. SAT® is a registered trademark of the College Board, which was not involved in the production of, and does not endorse this product. ACT® is a registered trademark of ACT, Inc., which was not involved in the production of, and does not endorse, this product. GMAT® is a registered trademark of the Graduate Management Admission Council®, which was not involved in the production of, and does not endorse, this product. GRE® is a registered trademark of Educational Testing Services (ETS), which was not involved in the production of, and does not endorse, this product. What makes one strand leading or lagging in replication?During DNA replication, one new strand (the leading strand) is made as a continuous piece. The other (the lagging strand) is made in small pieces. DNA replication requires other enzymes in addition to DNA polymerase, including DNA primase, DNA helicase, DNA ligase, and topoisomerase.
What causes leading and lagging strands?Due to the antiparallel orientation of the two chromosomal DNA strands, one strand (leading strand) is replicated in a mostly processive manner, while the other (lagging strand) is synthesized in short sections called Okazaki fragments.
What is the replication on the lagging strand known as?Lagging strand:
Chunks of DNA, called Okazaki fragments, are then added to the lagging strand also in the 5' to 3' direction. This type of replication is called discontinuous as the Okazaki fragments will need to be joined up later.
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Which of the following particular characteristics of DNA replication causes the leading strand to be constructed more quickly than the lagging strand?
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